Establishment of Tsc1flox / flox-GFAP-Cre (Tsc1GFAP CKO) mice for evaluating potential new antiepileptic therapies for tuberous sclerosis complex
S. C. LEISER1, A GHAVAMI2, M KWAN2, J BELTRAN2, D SONG1, D. M. DEVILBISS1, M WONG3, N RENSING3, S. L. ROBERDS4, D BRUNNER4 1Translational EEG, PsychoGenics Inc., Tarrytown, NY, USA; 2PsychoGenics Inc., Montvale, NJ, USA; 3Dept. of Neurol., Washington Univ. Sch. of...Translational Utility of the Mismatch Negativity: Implementing MMN in rats for Drug Discovery
D BREGNA1, D. R. ANDERSON2, T PISER2, S. C. LEISER1 1Translational EEG, PsychoGenics Inc., Tarrytown, NY, USA; 2Cadent Tx, Cambridge, MA, USA; Mismatch negativity (MMN) is a validated, objective measure of central auditory processing and has become a key clinical...
Post-traumatic stress disorder in the controlled cortical impact model of brain injury
A. M. CHOO1, S DAVIS1, M LANG1, A BARBOZA1, M OSBORNE1, Q CHANG1, T HANANIA1 1PsychoGenics Inc., Tarrytown, NY, USA Traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD) are often associated with each other. Comorbidity of TBI and PTSD are often seen...
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