SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D2 Receptor Mechanism of Actions
Dedic N, Jones P.G, Hopkins S.C, Lew R, Shao L, Campbell J. E, Spear K. L, Large T. H, Campbell U. C, Hanania T, Leahy E, Koblan K Journal of Pharmacology and Experimental Therapeutics. August 1, 2019 jpet.119.260281. For the past 50 years, the clinical efficacy of...
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease
Zeitler B, Froelich S, Marlen K, Shivak D.A, Yu Q, Li D, Pearl J.R, Miller J.C, Zhang L, Paschon D.E, Hinkley S.J, Ankoudinova I, Lam S, Guschin D, Kopan L, Cherone J.M, Nguyen B.H.O, Qiao G, Ataei Y, Mendel M.C, Amora R, Surosky R, Laganiere J, Vu B.J , Narayanan A,...
Validated Phenotypic Approach to Neuropsychiatric Drug Discovery
Leahy E Drug Development & Delivery March 2019 Vol 19 No 2: 46-49. At the recent American College of Neuropsychopharmacology (ACNP) meeting, Sunovion Pharmaceuticals and PsychoGenics Inc. announced positive Phase 2 results for SEP-363856, a novel, first-in-class...
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